Failed transfer of passive immunity is a component cause of pre-weaning disease in beef and dairy calves: A systematic review and meta-analysis


 Pre-weaned beef and dairy calves that fail to receive mater­nal antibodies are more susceptible disease. A systematic review meta-analysis were performed evaluate the as­sociation between failed transfer of passive immunity (FTPI) disease in pre-weaned calves. Three data­bases searched for relevant studies evaluated diagnosed with FTPI at ≤8 days age recorded incidence pre-weaning. Twenty-three, out 182 identified ref­erences, contained 46 studies. Twelve stud­ies effect on morbidity, 18 mortality, 8 diarrhea, pneumonia. Forty-two (91.3%) reported greater risk among The strength association var­ied was not resolved by subgrouping outcome, animal type, test, cut-off point, or cumulative Failed is a component cause calf may have impact some popula­tions than others.